This paper presents an enhanced ontology formalization, combining previous work in Conceptual Structure Theory and Order-Sorted Logic. Most existing ontology formalisms place greater importance on concept types, but in this paper we focus on relation types, which are in essence predicates on concept types. We formalize the notion of ‘predicate of predicates’ as meta-relation type and introduce the new hierarchy of meta-relation types as part of the ontology definition. The new notion of closure of a relation or meta-relation type is (...) presented as a means to complete that relation or meta-relation type by transferring extra arguments and properties from other related types. The end result is an expanded ontology, called the closure of the original ontology, on which automated inference could be more easily performed. Our proposal could be viewed as a novel and improved ontology formalization within Conceptual Structure Theory and a contribution to knowledge representation and formal reasoning (e.g., to build a query-answering system for legal knowledge). (shrink)

Scholars of early Chinese philosophy frequently point to the nontranscendent, organismic conception of the cosmos in early China as the source of China's unique perspective and distinctive values. One would expect recent works in Confucian ethics to capitalize on this idea. Reviewing recent works in Confucian ethics by P. J. Ivanhoe, David Nivison, R. P. Peerenboom, Henry Rosemont, and Tu Wei-Ming, the author analyzes these new studies in terms of the extent to which their representation of Confucian ethics reflects and (...) is consistent with the view that in early China the cosmos was conceived to be organismic, nontranscendent, and nondualistic. (shrink)

BackgroundResponsive neurostimulation has been utilized as a treatment for intractable epilepsy. The RNS System delivers stimulation in response to detected abnormal activity, via leads covering the seizure foci, in response to detections of predefined epileptiform activity with the goal of decreasing seizure frequency and severity. While thalamic leads are often implanted in combination with cortical strip leads, implantation and stimulation with bilateral thalamic leads alone is less common, and the ability to detect electrographic seizures using RNS System thalamic leads is (...) uncertain.ObjectiveThe present study retrospectively evaluated fourteen patients with RNS System depth leads implanted in the thalamus, with or without concomitant implantation of cortical strip leads, to determine the ability to detect electrographic seizures in the thalamus. Detailed patient presentations and lead trajectories were reviewed alongside electroencephalographic analyses.ResultsAnterior nucleus thalamic leads, whether bilateral or unilateral and combined with a cortical strip lead, successfully detected and terminated epileptiform activity, as demonstrated by Cases 2 and 3. Similarly, bilateral centromedian thalamic leads or a combination of one centromedian thalamic alongside a cortical strip lead also demonstrated the ability to detect electrographic seizures as seen in Cases 6 and 9. Bilateral pulvinar leads likewise produced reliable seizure detection in Patient 14. Detections of electrographic seizures in thalamic nuclei did not appear to be affected by whether the patient was pediatric or adult at the time of RNS System implantation. Sole thalamic leads paralleled the combination of thalamic and cortical strip leads in terms of preventing the propagation of electrographic seizures.ConclusionThalamic nuclei present a promising target for detection and stimulation via the RNS System for seizures with multifocal or generalized onsets. These areas provide a modifiable, reversible therapeutic option for patients who are not candidates for surgical resection or ablation. (shrink)

This is part 1 of 6 of the dossier What Do We Talk about when We Talk about Queer Death?, edited by M. Petricola. The contributions collected in this article sit at the crossroads between thanatology and queer theory and tackle questions such as: how can we define queer death studies as a research field? How can queer death studies problematize and rethink the life-death binary? Which notions and hermeneutic tools could be borrowed from other disciplines in order to better (...) define queer death studies? The present article includes the following contributions: – MacCormack P., What does queer death studies mean?; – Radomska M., On queering death studies; – Lykke N., Death as vibrancy; – Hillerup Hansen I., What concreteness will do to resolve the uncertain; – Olson P., Queer objectivity as a response to denials of death; – Manganas N., The queer lack of a chthonic instinct. (shrink)

© Ginn et al. 2016.The indexing methods currently used for serial femtosecond crystallography were originally developed for experiments in which crystals are rotated in the X-ray beam, providing significant three-dimensional information. On the other hand, shots from both X-ray free-electron lasers and serial synchrotron crystallography experiments are still images, in which the few three-dimensional data available arise only from the curvature of the Ewald sphere. Traditional synchrotron crystallography methods are thus less well suited to still image data processing. Here, a (...) new indexing method is presented with the aim of maximizing information use from a still image given the known unit-cell dimensions and space group. Efficacy for cubic, hexagonal and orthorhombic space groups is shown, and for those showing some evidence of diffraction the indexing rate ranged from 90% to 151%. Here, the indexing rate refers to the number of lattices indexed per image. (shrink)

DBS Think Tank IX was held on August 25–27, 2021 in Orlando FL with US based participants largely in person and overseas participants joining by video conferencing technology. The DBS Think Tank was founded in 2012 and provides an open platform where clinicians, engineers and researchers can freely discuss current and emerging deep brain stimulation technologies as well as the logistical and ethical issues facing the field. The consensus among the DBS Think Tank IX speakers was that DBS expanded in (...) its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. After collectively sharing our experiences, it was estimated that globally more than 230,000 DBS devices have been implanted for neurological and neuropsychiatric disorders. As such, this year’s meeting was focused on advances in the following areas: neuromodulation in Europe, Asia and Australia; cutting-edge technologies, neuroethics, interventional psychiatry, adaptive DBS, neuromodulation for pain, network neuromodulation for epilepsy and neuromodulation for traumatic brain injury. (shrink)

© 2015, Springer-Verlag Berlin Heidelberg.Genetic studies have identified single nucleotide polymorphisms associated with the risk of prostate cancer. It remains unclear whether such genetic variants are associated with disease aggressiveness. The NCI-SPORE Genetics Working Group retrospectively collected clinicopathologic information and genotype data for 36 SNPs which at the time had been validated to be associated with PC risk from 25,674 cases with PC. Cases were grouped according to race, Gleason score and aggressiveness. Statistical analyses were used to compare the frequency (...) of the SNPs between different disease cohorts. After adjusting for multiple testing, only PC-risk SNP rs2735839 was significantly and inversely associated with aggressive and high-grade disease in European men. Similar associations with aggressive and high-grade disease were documented in African-American subjects. The G allele of rs2735839 was associated with disease aggressiveness even at low PSA levels in both European and African-American men. Our results provide further support that a PC-risk SNP rs2735839 near the KLK3 gene on chromosome 19q13 may be associated with aggressive and high-grade PC. Future prospectively designed, case-case GWAS are needed to identify additional SNPs associated with PC aggressiveness. (shrink)

Abstract In this essay, a new approach for the ethical study of emerging technology ethics will be presented, called anticipatory technology ethics (ATE). The ethics of emerging technology is the study of ethical issues at the R&D and introduction stage of technology development through anticipation of possible future devices, applications, and social consequences. I will argue that a major problem for its development is the problem of uncertainty, which can only be overcome through methodologically sound forecasting and futures studies. I (...) will then consider three contemporary approaches to the ethics of emerging technologies that use forecasting: ethical technology assessment, the techno-ethical scenarios approach and the ETICA approach, and I considered their strengths and weaknesses. Based on this critical study, I then present my own approach: ATE. ATE is a conceptually and methodologically rich approach for the ethical analysis of emerging technologies that incorporates a large variety of ethical principles, issues, objects and levels of analysis, and research aims. It is ready to be applied to contemporary and future emerging technologies. Content Type Journal Article Category Original Paper Pages 1-13 DOI 10.1007/s11569-012-0141-7 Authors Philip A. E. Brey, Department of Philosophy, School of Behavioral Sciences, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands Journal NanoEthics Online ISSN 1871-4765 Print ISSN 1871-4757. (shrink)

BackgroundThe ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are widely endorsed but compliance is limited. We sought to determine whether journal-requested completion of an ARRIVE checklist improves full compliance with the guidelines.MethodsIn a randomised controlled trial, manuscripts reporting in vivo animal research submitted to PLOS ONE (March–June 2015) were randomly allocated to either requested completion of an ARRIVE checklist or current standard practice. Authors, academic editors, and peer reviewers were blinded to group allocation. Trained reviewers performed outcome adjudication (...) in duplicate by assessing manuscripts against an operationalised version of the ARRIVE guidelines that consists 108 items. Our primary outcome was the between-group differences in the proportion of manuscripts meeting all ARRIVE guideline checklist subitems.ResultsWe randomised 1689 manuscripts (control: n = 844, intervention: n = 845), of which 1269 were sent for peer review and 762 (control: n = 340; intervention: n = 332) accepted for publication. No manuscript in either group achieved full compliance with the ARRIVE checklist. Details of animal husbandry (ARRIVE subitem 9b) was the only subitem to show improvements in reporting, with the proportion of compliant manuscripts rising from 52.1 to 74.1% (X2 = 34.0, df = 1, p = 2.1 × 10−7) in the control and intervention groups, respectively.ConclusionsThese results suggest that altering the editorial process to include requests for a completed ARRIVE checklist is not enough to improve compliance with the ARRIVE guidelines. Other approaches, such as more stringent editorial policies or a targeted approach on key quality items, may promote improvements in reporting. (shrink)

Physicalism dominated Anglo‐American philosophy in the latter half of the twentieth century, and is perhaps still the most popular view among analytic philosophers. Panpsychism is increasingly being seen as a serious option, both for explaining consciousness and for providing a satisfactory theory of the natural world. Perhaps the most popular form of panpsychism at present is constitutive panpsychism. At least some fundamental material entities are conscious; facts about human and animal consciousness are grounded in facts about the consciousness of their (...) fundamental material parts. This chapter equates panpsychism with constitutive panpsychism. In considering responses to the notorious combination problem for panpsychism, the chapter moves onto other forms of panpsychism to examine whether they fare any better against this challenge. It adopts the via negativa definition of physicalism. Panqualityism is the only form of panprotopsychism which offers a clear positive proposal as to what protophenomenal properties are. (shrink)

PHOTO ID 121339257© Designer491| Dreamstime.com ABSTRACT When physicians use their clinical knowledge and skills to advance the well-being of their patients, there may be apparent conflict between patient autonomy and physician beneficence. We are skeptical that today’s medical ethics education adequately fosters future physicians’ commitment to beneficence, which is both rationally defensible and fundamentally consistent with patient autonomy. We use an ethical dilemma that was presented to a group of third-year medical students to examine how ethics education might be causing (...) them to give undue deference to autonomy, thereby undermining their commitment to beneficence. INTRODUCTION The right of patients to choose which treatments they prefer is rooted in today’s social mores and taught as a principle of medical ethics as respect for autonomy. Yet, when physicians use their clinical knowledge and skills to advance the well-being of their patients, there may be a conflict between patient autonomy and physician beneficence. We are skeptical that today’s medical ethics education adequately fosters a commitment to beneficence, which is both rationally defensible and fundamentally consistent with patient autonomy. I. An Ethical Dilemma The impetus for this paper arose when students who were completing their third clinical year discussed a real-life ethical dilemma. A middle-aged man developed a pulmonary hemorrhage while on blood thinners for a recently placed coronary stent. The bleeding was felt to be reversible, but the patient needed immediate intubation or he would die. The cardiologist was told that the patient previously expressed to other physicians that he never wanted to be intubated. However, the cardiologist made the decision to intubate the patient anyway, and the patient eventually recovered.[1] Students were asked if they believed that the cardiologist had acted ethically. Their overwhelming response was, “No, the patient should have been allowed to die.” We looked into how students applied ethical reasoning to conclude that this outcome was ethically preferred. To explore how the third-year clinical experience might have formed the students’ judgment, we presented the same case to students who were just beginning their third year. Their responses were essentially uniform in recommending intubation. While there is likely more than one reasonable view in this case, we agree with the physician and the younger medical students that intubation was the ethically appropriate decision and will present an argument for it. But first, we explain the reasoning behind the more advanced medical students’ decision to choose patient autonomy at the expense of beneficence. II. Medical Ethics Education and the Priority of Autonomy Beauchamp and Childress’s Principles of Biomedical Ethics, first published in 1979 and now in its 8th edition, is a significant part of the formal ethics education in medical school.[2] Students learn an ethical decision-making approach based on respect for four ethical principles: autonomy, beneficence, nonmaleficence, and justice. While Beauchamp and Childress officially afford no prima facie superiority to any principle, the importance of respect for patient autonomy has increased through the editions of their book. For example, early editions of their book opposed the legalization of physician-assisted death compared to recent editions that defended it.[3] As another example, Beauchamp and Childress make paternalism harder to justify by adding an autonomy-protecting condition to the list of conditions for acceptable paternalism.[4] Authority, they contend, need not conflict with autonomy—provided the authority is autonomously chosen.[5] “The main requirement,” they write, “is to respect a particular patient’s or subject’s autonomous choices, whatever they may be.[6] In the principlism of Beauchamp and Childress, autonomy now seems to have a kind of default priority.[7] However, the bioethics discourse has strong counternarratives, noting some movement to elevate the role of beneficence and to respect the input of stakeholders, including the family and the healthcare team. Ethics education achieves particular relevance in the third clinical year when students become embedded in the care of patients and learn from what has been called the informal curriculum. They observe how attending physicians approach day-to-day ethical problems at the patient’s bedside. In this context, students observe the importance of informed consent for serious treatments or invasive procedures, a practice that highlights the principle of patient autonomy. In both the formal and informal curriculum, medical students observe how, in the words of Paul Wolpe, “patient autonomy has become the central and most powerful principle in ethical decision-making in American medicine.”[8] In short, students appear to learn a deference for patient autonomy. This curricular shift in favor of autonomy coincides with legal developments that protect patients’ rights and decision-making with respect to their healthcare choices. The priority of autonomy in medicine benefits patients by reflecting their choices and, in some cases, their fundamental liberty. III. The Practice of Medicine and the Commitment to Beneficence There are many critiques of the dominant place that autonomy has in biomedical ethics,[9] especially considering that autonomy seems to be biased toward individualistic, Western, and somewhat American culture-driven values.[10] In addition, many bioethical dilemmas are cast as a conflict between autonomy and beneficence. Our point is that medical students bring to their study of medicine a commitment to beneficence that seems to be suppressed by practical ethics education. We think this commitment is rationally defensible and should be nurtured. It is striking that young medical students have a pre-reflective commitment to beneficence at all. For, as we mentioned, it is not just medicine but Western culture generally that prioritizes autonomy in settling ethical dilemmas. In wanting to act for the good of others (rather than simply agreeing to what others want), physicians are already swimming somewhat against the cultural tide.[11] However, doing so makes sense, given the nature of medicine and the profession of healing. When prospective medical students are asked why they wish to become physicians, the usual answer is some variation on caring for the sick and preventing disease. It is unlikely that a reason to become a physician is to respect a patient’s autonomy. It would be easy to dismiss medical students’ commitment to beneficence as a mere intuition and contrary to a more reasoned and deliberative approach. Beauchamp and Childress seem to minimize the value of physician intuition, stating that justifications for certain procedures are “…supported by good reasons. They need not rest merely in intuition or feeling.”[12] Henry Richardson writes that “situational or perceptive intuition…leaves the reasons for decision unarticulated.”[13] We think this is a crude and rather thin way of understanding intuition. Some bioethicists have defended intuition as essential to the practice of medicine and not something opposed to reason.[14] In the case we describe, we believe the ethical justifications s for the patient’s intubation are fundamentally sound: the patient did not have a “do not intubate” order written in the chart, the emergency intubation had not been foreseen, so the patient did not have the opportunity to consent to or reject intubation; the patient had consented to the treatment for his cardiac disease so his consent for intubation could have been assumed;[15] and the consequences of respecting his autonomy did not justify allowing him to die.[16] While it is possible to have more than one reasonable view on this case, we think the case for beneficence is strong and certainly should not be dismissed out of hand. We do not deny that if a patient makes a clearly documented, well-informed decision to forgo intubation that this decision ought to be respected by the physician (even if the physician disagrees with the patient’s decision). But, in this situation, as in many others in the practice of medicine, the patient’s real wishes and preferences are not well-articulated in advance. There are many cases where a physician acts based on what she believes the patient, or the surrogate, would want, sometimes in situations that do not allow much time for reflection. An example might be resuscitation of a newborn at the borderline of viability. In their ethics education, beneficence would mean acting first to save a life. If the patient or surrogate makes an informed decision to the contrary, a beneficent physician respects that autonomous decision. In the case presented, the patient expressed gratitude to the cardiologist when extubated. But what if he had expressed anger at the physician for violating his autonomy? There are those who could argue that not only was intubation ethically wrong but that the cardiologist put himself in legal jeopardy by his actions (especially if there had been a written refusal applicable to the specific situation). In the example we use, we point out that the cardiologist may not have escaped a lawsuit if the patient had died without intubation. His family, when hearing the circumstances, may have sued for failure to act and dereliction of the cardiologist’s duty to save him. Beyond a potential legal challenge for either action or inaction, there is an overriding ethical question the cardiologist had to address: what course would be most satisfying to his conscience? Would he rather allow a patient to die for fear of recrimination, or act to save his life, regardless of the personal consequences? In the absence of real knowledge about the patient’s considered wishes, it is most reasonable to err on the side of promoting patient well-being. A physician’s commitment to beneficence is not necessarily a way of undermining a patient’s autonomy. In acting for the patient's good, physicians are also acting on what it is reasonable to believe a patient (or most patients, perhaps) would want, which is obviously connected to what a patient does want. Pellegrino and Thomasma argue that beneficence includes respect for a patient’s autonomy since “the best interests of the patient are intimately linked with their preferences.”[17] Instead of conceptualizing ethical dilemmas in medicine as conflicts between autonomy and beneficence, it is possible that medical schools could teach students that truly practicing beneficence is a way of valuing patient autonomy, especially when the patient’s wishes are not specific to the situation and are not clearly expressed. CONCLUSION It is important for students and practicing physicians to understand the principle of respect for patient autonomy in a pluralistic society that demands personal self-determination. However, the role of the physician as a beneficent healer should not be diminished by this respect for autonomy. Respecting a patient’s autonomy is grounded in and manifested by physician beneficence.[18] That is, seeking what is good for the patient can only be good if it respects their personhood and dignity. We propose that a commitment to beneficence, incipient in young medical students, should be developed over time with their other clinical reasoning skills. Such a commitment need not be sacrificed on the altar of patient autonomy. Beneficence needs greater relative moral weight with students as they proceed in their ethics education. - [1] S. Jauhar, “When Doctors Need to Lie,” New York Times, February 22, 2014, https://www.nytimes.com/2014/02/23/opinion/sunday/when-doctors-need-to-lie.html. [2] T. L. Beauchamp and James F. Childress, Principles of Biomedical Ethics, 8th ed. (New York, NY: Oxford University Press, 2019). [3] Louise A. Mitchell, “Major Changes in Principles of Biomedical Ethics,” The National Catholic Bioethics Quarterly 14, no. 3 (2014): 459–75, https://doi.org/10.5840/ncbq20141438. [4] Tom L. Beauchamp and James F. Childress, Principles of Biomedical Ethics, 8th ed. (New York, NY: Oxford University Press, 2019), 238. [5] Beauchamp and Childress, 103. [6] Beauchamp and Childress, p. 108. [7] For other accounts that prioritize autonomy, see e.g. Allen E. Buchanan and Dan W. Brock, Deciding for Others: The Ethics of Surrogate Decision Making (Cambridge University Press, 1989), 38–39; R Gillon, “Ethics Needs Principles—Four Can Encompass the Rest—and Respect for Autonomy Should Be ‘First among Equals,’” Journal of Medical Ethics 29, no. 5 (October 2003): 307–12, https://doi.org/10.1136/jme.29.5.307. For examples of critiques of these accounts, see footnote 9. [8] P. R. Wolpe, “The Triumph of Autonomy in American Bioethics: A Sociological View,” in Bioethics and Society: Constructing the Ethical Enterprise, p. 43. [9] V. A. Entwistle et al., “Supporting Patient Autonomy: The Importance of Clinician-Patient Relationships,” Journal of General Internal Medicine 25, no. 7 (July 2010): 741–45; C. Foster, Choosing Life, Choosing Death: The Tyranny of Autonomy in Medical Ethics and Law, 1st ed. (Oxford ; Hart Publishing, 2009); O. O’Neill, Autonomy and Trust in Bioethics, The Gifford Lectures, University of Edinburgh 2001 (Cambridge, UK: Cambridge University Press, 2002). [10] P. Marshall and B. Koenig, “Accounting for Culture in a Globalized Bioethics,” The Journal of Law, Medicine & Ethics: A Journal of the American Society of Law, Medicine & Ethics 32, no. 2 (2004): 252–66; R. Fan, “Self-Determination vs. Family-Determination: Two Incommensurable Principles of Autonomy,” Bioethics 11, no. 3–4 (1997): 309–22. [11] Arguments stressing the importance of beneficence, as ours does here, certainly approach paternalistic arguments. We set aside the complex issue of paternalism for purposes of this paper and simply note that the principle of beneficence as such does not say anything specifically about acting against the patient’s will. In the case study that focuses this paper, we do not believe the patient’s will or wishes were clearly indicated. [12] Beauchamp and Childress, Principles of Biomedical Ethics, p. 20, see note 2 above. [13] H. S. Richardson, “Specifying, Balancing, and Interpreting Bioethical Principles,” The Journal of Medicine and Philosophy: A Forum for Bioethics and Philosophy of Medicine 25, no. 3 (January 1, 2000): 285–307, p. 287. [14] H. D. Braude, Intuition in Medicine a Philosophical Defense of Clinical Reasoning (Chicago ; University of Chicago Press, 2012). [15] R. Kukla, “Conscientious Autonomy: Displacing Decisions in Health Care,” The Hastings Center Report 35, no. 2 (2005): 34–44. [16] M. Schermer, The Different Faces of Autonomy: Patient Autonomy in Ethical Theory and Hospital Practice, vol. 13, Library of Ethics and Applied Philosophy (Dordrecht: Springer Netherlands, 2002). [17] E. D. Pellegrino and D. C. Thomasma, For the Patient’s Good - the Restoration of Beneficence in Health Care (New York, NY: Oxford University Press, 1988), p. 29. [18] Pellegrino and Thomasma, For the Patient’s Good. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviews  YOURS FAITHFULLY P L. T Religious Studies / McGill U. Montreal, , Canada   @-.. Ray Perkins, Jr., ed. Yours Faithfully, Bertrand Russell: a Lifelong Fight for Peace, Justice, and Truth in Letters to the Editor. Chicago and La Salle, Ill.: Open Court, . Pp. xii, . .; pb .. lthough Bertrand Russell was obviously a prolific writer on numerous Atopics (technical philosophy, education, religion, political (...) critique, women ’s rights, and nuclear disarmament), and published his views through various venues such as technical volumes, popular books, essays, scholarly articles, reviews, and pamphlets, there has been a neglect of Russell’s utilization of the newspaper’s “Letters to the Editor” section. In this accessible volume, Ray Perkins has collected and organized the letters to the editor published by Russell. Russell, from the first known letter in  to the final public statement on the Middle East crisis published posthumously in , published approximately  letters to the editor. Of these  are published in Yours Faithfully. Perkins begins with a helpful introduction (pp. –), placing the letters into the broader framework of Russell’s life. We are introduced, in a very basic sketch, to the development of Russell’s thought, encountering such major threads in Russell’s life as his early political interests (indicated in  with German Social Democracy, though pushed to the foreground with the First World War) and the developments in his philosophical theories from Principia Mathematica through Our Knowledge of the External World to Human Knowledge. We also meet various significant individuals in Russell’s life, such as his various wives and his colleagues both in philosophy and in activist work. Although Russell scholars will find this introduction somewhat simplistic, those non-specialists encountering Russell through this book will find the introduction helpful and clearly necessary in order to contextualize the letters.  Reviews The letters themselves are organized into chronological chapters. The first eight letters, “Early Letters”, are dated from  to . These are the earliest known published letters by Russell. Perkins then gives us those letters published during the First World War (–). The remaining letters fall into: “Between the Wars” (–); “World War Two and the Early Cold War” (–); “The Cold War and the Nuclear Peril” (–); and “The Cold War and American Militarism” (–). The final document is Russell’s posthumous  statement to the Conference of Parliamentarians in Cairo. Each chapter has a brief overview of the period in Russell’s life, further situating the letters. Perkins is also careful to offer introductions to each letter, and the occasional footnote to explain various references in the letters (names of individuals that may not be familiar to readers, major events referred to, etc.). Each letter is numbered sequentially, accompanied by the B&R number of the letter. Given Russell’s diverse interests, clearly reflected in these letters, Perkins has subdivided the last four chapters into thematic subsections. Those readers who are interested in Russell’s views on, e.g., religion, education, or Vietnam can find the relevant letters with ease. A comprehensive index also makes the collection accessible. The exact division of the chapters tends to reflect major shifts in Russell’s thinking as much as historical developments (the latter obviously affecting the former in any case). For example, the – break reflects both Russell’s move from England to the  and his departure from the pacifist stance of Which Way to Peace? The – break reflects Russia’s development of nuclear weapons and Russell’s shift towards mutual disarmament by both superpowers. And the – break reflects Russell’s intervention in the Cuban Missile Crisis as well as his reactions to the  involvement in Vietnam. Perkins has supplied us with an excellent collection of letters. Although some may ask how useful such a collection may be, I would contend that the letters are vital sources of information for Russell studies. First, from an historian’s perspective, the preservation and accessibility of primary material is a noble and worthwhile achievement. Perkins is to be commended for his efforts in drawing our attention to this material by blowing the dust off material that most would ignore. Second, the letters themselves are fascinating indications of shifts in Russell’s thinking, pointing out the nuances of such shifts as he engages in debate with various other voices over... (shrink)

Moral philosophy and education, by H. D. Aiken.--The moral sense and contributory values, by C. I. Lewis.--Realms of value, by P. W. Taylor.--The role of value theory in education, by J. D. Butler.--Does ethics make a difference? By K. Price.--Educational value statements, by C. Beck.--Educational values and goals, by W. K. Frankena.--Conflicts in values, by H. S. Broudy.--Levels of valuational discourse in education, by J. F. Perry and P. G. Smith.--Education and some moves toward a value methodology, by A. S. (...) Clayton.--You can't pray a lie, by M. Twain.--Men, machines, and morality, by J. F. Soltis.--Teaching and telling, by I. Scheffler.--Reason and habit, by R. S. Peters.--The two moralists of the child, by J. Piaget.--Causes and morality, by R. S. Peters.--On education and morals, by R. W. Sleeper.--Moral autonomy and reasonableness, by T. D. Perry. (shrink)

There is an intuition, notoriously difficult to formalise, that only some predicates express real properties. J. M. Dunn formalises this intuition with relevance logic, proposing a notion of relevant predication. For each first order formula Ax, Dunn specifies another formula that is intuitively interpreted as "Ax expresses a real property". Chapter I calls such an approach an object language approach, since the claim that Ax expresses a real property is rendered as a formula in the object language. On a metalanguage (...) approach, on the other hand, the claim that Ax expresses a real property would be metalinguistic, mentioning but not using the formula Ax. ;Our Introduction begins by investigating Dunn's motivation for relevant predication, and argues that it implicitly presupposes some interpretation of identity. Indeed, part of the dissertation's work is to use relevant predication as a key to a coherent account of relevant identity. ;Chapter I re-motivates relevant predication. We consider P. Geach's distinction between real and "Cambridge" change, and suggest that there is an underlying distinction between real and Cambridge predicates. We further argue that no classical object language approach can formalise this distinction. So we turn to relevance logic, remotivating relevant predication, with Geach's distinction in mind. ;In light of this new motivation, we argue that relevant prediction relies on a logically weak notion of identity, according to which "x = y" means "x and y share all relevant properties". Identity is taken up in a more technical setting in Chapters IV and V. ;Subsequent chapters investigate technical issues that flow from Chapter I. Chapter II investigates metalinguistic grammatical characterisations of relevant predication. Chapter III concerns the semantics of first order relevance logic. Chapter IV investigates the identity in R and its relationship to relevant predication. In particular, Chapter IV argues against introducing the axiom, $\to$ Ay), in relevance logic, since the resulting systems are unstable, in a sense motivated by the notion of relevant identity underlying Dunn's notion of relevant predication. Finally Chapter V investigates the possibility of a coherent theory of identity in R's modal relatives ${\bf R}\sp\square$ and E. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:BOOK REVIEWS 95 direction, it opens a field of pure philosophy, unencumbered by surds such as finite man. Only if the Phenomenology is taken as a monographic work on man can there be difficulty. Let us hasten to add that, on the very premises of his book, Loewenberg's criticism of Hegel is tentative rather than apodictic; its harshness is relieved through the dialogue form. And perhaps, the interlocutors will, (...) as one of them suggests, "resume (their) conversations with fresh minds at a later date" (p. 371). They might find that they have to go beyond the limits of exoteric discussion. Or, conversely, they might find that exoteric treatment can yield no more than an anthropological reading and is, in fact, bound up with it. If Loewenberg 's extant commentary did no more than demonstrate this negative point, however implicitly,it would be of great merit. But there is of course much more: there is the substance of Loewenberg's commentary, largely unaffected by the above counter-representations. Theoretical problems aside, the supreme value of the book lies in its clarity and perceptiveness, in the "sense" it makes of the Phenomenology. Of a kind all its own, it will henceforth serve as the preferred entrance to Hegel. KLAUS HARTMANN Bonn, W. Germany Arthur Hfibscher, editor. XXXVIlI. Schopenhauer-Jahrbuch ]~r das Jahr 1957. (Frankfurt/ Main: Waldemar Kramer, 1967.Pp. v + 244.) Schopenhauer: Philosophe de l'Absurde. By Clement Brosset. (Paris: Presses Universitaires de France, 1967.Pp. ix [i] -b 107.Paper, F. 7.--) Manches in dem Jahrbuch ist rein anekdotisch; manches bio- oder bibliographisch. Einiges h~ngt nur sehr lose mit Schopenhauer zusammen; so der liingste Beitrag (K. Engisch, "Todesstrafe--ja oder nein?,") mit nfitzlicher historischer und systematiseher Ubersieht, die zum Ergebnis kommt, dass die Argumente gegen die Todesstrafe iiberwiegen. Von gesetzgeberischen Interessen getragen ist such G. Zoebe, "Sind die Tiere rechtlos?" Der zweitliingste Beitrag (H. Voigt, 'r0ber Schopenhauers Erkenntnistheorie,') enth~ilt eine Art von Variationen sum Thema des Zusammenhanges zwischen Charakter und Schicksah Man freut sich, dass ein Inder (Kanti Chandra Pandey) sich fiber Schopenhauers Kenntnis des Hinduismus und Buddismus eehr anerkennendausspricht. Das Bild der Sehopenhauerschen Philosophie, wie es uns im Jahrbuch begeguet ist das uns vertraute: Pessimismus, ErlSsung durch Kunst, Mitleid, Verneinung des Willens. Aber nach Brosset erfassen diese Kategorien nur die sekund~ren Charaktere der Schopenhauerschen Philosophie. In ihrem wirklich wertvollen Kern sei diese Philosophie erstens Vorl~uferin der yon Brosset so genannten genealogischen Philosophie eines Marx, Nietzsche und Freud; allerdings letzten Endes ein Versager, da sie auf das eigentliche Anliegen der genealogischen Philosophie, n~mlich die Ableitung konkreter und spezifischer Ideen (bei Schopenhauer: der Intelligenz) aus der Umformung unbewusster Tatbestiinde (bei Schopenhauer: des Willens), nicht eingehe, sondern sich mit der Feststellung begniigt, dass die Wurzel der (bewussten) InteUigenz der (unbewusste) Wille ist. Zweitens sei Schopenhauer der erste, der seine Philosophie auf der Urerfahrung der Grundlosigkeit (Brosset zieht den Ausdruck Absurdit~t vor), daher Unausdenkbarkeit oder Unergrfindlichkeit des Seins im ganzen, aufbaut. Auf diese Erfahrung (die Frage, 'Warum nicht Nichts?' ist unbeantwortbar) reagiere der Menseh mit Angst. Die Notwendigkeit und die Zweckm~issigkeit, die die Welt im ganzen charskterisieren, seien selbst kontingent und zwecklos. Manchmal scheint mir Brosset die Originalitiit seiner Interpretationen zu iiberseh~tzen; insbesondere seine Erkl~rung der Blindheit des Willens (S. 26f.) rennt wohl offene Tfiren ein. PHILIP MERLAN ~cripps College, Claremont, California... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Religion and Philosophy from Plato's Phaedo to the Chaldaean Oracles PHILIP MERLAN A FEW YEARSAGO another of the so-called Orphic tablets was found? Like the previously known ones~it is an instruction for the deceased--it tells him what he will find in the beyond and how he is to act to secure for himself a blessed afterlife. As a rule the tablets differ somewhat in their wording and the (...) newly found is particularly remarkable in that the deceased, when asked by the guards of the Spring of Memory what his business here is, is instructed to answer, "I am a child of the Earth and o~octvo~5~aveOo~v~og ~ and my name is Asterios. ''~ Now, it is generally recognized that the tablets are the product of some mystery religion? The new tablet suggests that part of its initiation ceremony might have been the experience of a mock death and a mock rebirth, the latter symbolized by the assuming of a new name? XN. M. Verdelis, "XaXr~ 7eCp6~oxos raX~rls ~x r 'ApxaLoXoy~K ~ 'Er 1950-1951 (Athens, 1951), pp. 80-105, esp. pp. 99-105. 2 Their text can be found in any edition of Diels-Kranz, VS. New finds: N. M. Verdelis, '0pr162 ~,&rt*ara ~ Kpr "Ap~ca~oXo*t~x~"E~tzep~ 1953-54, Second Part (Athens, 1958), pp. 56-60. On their character (Orphic? Pythagorean?), see F. Cumont, Lex perpetua (Paris, 1944), p. 406. Which mystery religion professed these two as obviously the highest deities? One is tempted to think of the mysteries of Samothrace, as in them these two deities played a conspicuous role according to Varro, De lingua lat. V 58 (cf. B. Cardauns, Varros 'Logistoricus' iiber die G6tterverehrung [Wiirzburg, 1960], pp. 60-67). 4 dar (~po4pro~)seems to me an evident conjecture by Verdelis. See, e.g., M. P. Nilsson, Geschichte der griechischen Religion, Vol. 2 (Miinchen, 1950), pp. 223-227. 0This is the assumption of Verdelis, XaXxr ~'e,~0~oxo~ with which I agree. On baptismal names see, e.g., A Oepke, "AM~IOAAEIY~ im griechischen und hellenistischen Kult," Archiv fiir Religionswissenschaft 31 (1934), pp. 42-56, esp. 52, note 5 (den Anstoss---scil. to bestowing of a new name on the initiate--gaben wohl primitive Wiedergeburtsgedanken). It seems to me that the Pindaric lines praising him who descends to the netherworld if he had been initiated, because he ot~e ~p fllov.reXew'gu,/olSeJ,~b.&6a~orol,tlpx~p (fr. 137a Sch) are to be explained by assuming that Pindar is here alluding to the experience of mock death (~-~,ev~-~) and mock rebirth (apX~), though it remains unclear whether the initiate experienced them in his own person or was only shown something (e.g. the burial of a seed followed by its shooting into an ear) symbolizing such events. [163] 164 HISTORY OF PHILOSOPHY And it is only natural to suppose that the initiation ceremony was preceded by some kind of ritual purification. In one more respect the new tablet is remarkable. It is the oldest we know. It belongs to the mid-fourth century. And this means that perhaps only a few years separate it from the date of the publication of Plato's Phaedo.' Now, as everybody knows, the Phaedo has something to say on mystery religions. Socrates first explains to his friends why he is not only not afraid of death but even looking forward to it. All his life long, he says, he was a philosopher and philosophy, as he sees it, is nothing else but ~X~-c~l0ctvd,ov. And as he explains in what way philosophy is a preparation for death, he time and again uses for the description of the philosopher's way of life the word 'pure' and its cognates (Phaedo 67d-e; 69a6-e5 [~d~}aqot~,•, ~xa0a0~vog], so that in the end the philosopher's way of life can by Socrates be described as purification-obviously purification not in its ritual sense of the word but, as Socrates sees it, in its true sense. And now Socrates clinches his argument and says: And it seems indeed that the men to whom we are indebted for the institution of... (shrink)

D.A. Armstrong’s account (1983, intimately influenced by Tooley 1977 and Swoyer 1982) of natural laws is that they arerelations between universals.Armstrong doesn’t simply hold that laws are some relationships or other between universals. He also holds that they are first-order universals themselves (1983, pp. 89-90). Each ordinary law-say,causallaw-is numerically identical to some first-order universal. This is a striking, seemingly incredible hypothesis. What is Armstrong thinking of when he says (1983, p. 90):I propose that the state of affairs, the law, N(F,G), (...) is a dyadic universal, that is, a relation, holding between states of affairs. Suppose that a particular object, a, is F, and so, because of the law N(F,G), it, a, is also G. This state of affairs, an instantiation of the law, has the form Rab, where R = N(F,G), a = a’s being F, and b, = b’s being G:(N(F,G))(a's being F, b's being G). (shrink)

This paper explores the truism that people think about what they say. It proposes that, to satisfy their own goals, people often plan their speech acts to affect their listeners' beliefs, goals, and emotional states. Such language use can be modelled by viewing speech acts as operators in a planning system, thus allowing both physical and speech acts to be integrated into plans. Methodological issues of how speech acts should be defined in a planbased theory are illustrated by defining operators (...) for requesting and informing. Plans containing those operators are presented and comparisons are drawn with Searle's formulation. The operators are shown to be inadequate since they cannot be composed to form questions (requests to inform) and multiparty requests (requests to request). By refining the operator definitions and by identifying some of the side effects of requesting, compositional adequacy is achieved.The solution leads to a metatheoretical principle for modelling speech acts as planning operators. (shrink)

What is involved when a group of agents decide to do something together? Joint action by a team appears to involve more than just the union of simultaneous individual actions, even when those actions are coordinated. We would not say that there is any teamwork involved in ordinary automobile traffic, even though the drivers act simultaneously and are coordinated (one hopes) by the traffic signs and rules of the road. But when a group of drivers decide to do something together, (...) such as driving somewhere as a convoy, it appears that the group acts more like a single agent with beliefs, goals, and intentions of its own, over and above the individual ones. [more]. (shrink)

This paper explores principles governing the rational balance among an agent's beliefs, goals, actions, and intentions. Such principles provide specifications for artificial agents, and approximate a theory of human action (as philosophers use the term). By making explicit the conditions under which an agent can drop his goals, i.e., by specifying how the agent is committed to his goals, the formalism captures a number of important properties of intention. Specifically, the formalism provides analyses for Bratman's three characteristic functional roles played (...) by intentions [7, 9], and shows how agents can avoid intending all the foreseen side-effects of what they actually intend. Finally, the analysis shows how intentions can be adopted relative to a background of relevant beliefs and other intentions or goals. By relativizing one agent's intentions in terms of beliefs about another agent's intentions (or beliefs'), we derive a preliminary account of interpersonal commitments. (shrink)

This book presents views of the concept of intention and its relationship to communication from three perspectives: philosphy, linguistics, and artificial intelligence. The book is a record of a workshop held in 1987.

Between the affirmative and the negative, the compositional and the oppositional, we need to rethink the difference between difference and contradiction. In this regard, the concept of ‘diplomacy’, as developed by Isabelle Stengers, is of particular significance. Whereas many adherents of an affirmative ontology of difference reduce contradiction to a caveat – ‘of course, antagonism is inevitable, but …’ – diplomacy makes contradiction its fundamental concern. This article explicates the significance of such a conception, via close readings of Stengers’ work (...) in relation to that of Gilles Deleuze, and Gottfried Wilhelm Leibniz. However, it also develops diplomacy in new directions, particularly relating the diplomatic ‘fold’ to the sovereign ‘cut’. The fold of coexistence, then, is achieved through diplomacy as a ‘labour of difference’, against ‘facile pluralism’, which takes worldly cohabitation as given. A diplomatic political ontology is neither bellicose nor pacific; rather, it dramatizes the possibility of peace from within a coercive historical reality. (shrink)

One of the most important recent developments in the discussion of Kierkegaard's ethics is an interpretation defended, in different forms, by Philip Quinn and Stephen Evans. Both argue that a divine-command theory of moral obligation is to be found in Works of Love . Against this view, I argue that, despite significant overlap between DCT and the view of moral obligation found in Works of Love , there is at least one essential difference between the two: the former, but (...) not the latter, is committed to the claim that, necessarily, p is morally obligatory only if God commands that p. (shrink)

Philip R. Shields shows that ethical and religious concerns inform even the most technical writings on logic and language, and that, for Wittgenstein, the need to establish clear limitations is both a logical and an ethical demand. Rather than merely saying specific things about theology and religion, major texts from the Tractatus to the Philosophical Investigations express their fundamentally religious nature by showing that there are powers which bear down upon and sustain us. Shields finds a religious view of (...) the world at the very heart of Wittgenstein's philosophy. "Shields argues that the appearance throughout Wittgenstein's writings of such concepts as ritual, limit, transgression, a change of will, pride, temptation, and judgment implies a relation between religion and the logical aspects of Wittgenstein's philosophy."-- Choice "Of the many recent books about Wittgenstein, Logic and Sin is one of the very few that are well worth having"--Fergus Kerr, Modern Theology "What Shields has uncovered in Wittgenstein's religious sensibility is something genuine and profound. . . . Shields has not just written an important book on Wittgenstein but an enlightening work that invites further reflection."--Eric O. Springsted, Cross Currents. (shrink)